BRD4 D1-IN-3
BRD4 D1-IN-3 (compound 39) is a potent, selective, and cell-active BRD4-D1 inhibitor (IC50 = 39 nM, Ki = 2.4 nM) with >1700-fold selectivity over BRD2-D1. BRD4 D1-IN-3 reduces the expression of pro-inflammatory chemokines CXCL1 and CCL2 in an LPS (HY-D1056)-mediated cellular model of liver inflammation. BRD4 D1-IN-3 can be used for liver inflammation research.
For research use only. We do not sell to patients.
- Formula: C28H26F3N5O
- Molecular Weight:505.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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BRD4-BD1 39 nM (IC50) |
BRD4-BD1 2.4 nM (Ki) |
BRD2-BD1 |
Chemical Information
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Molecular Weight 505.53
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Formula C28H26F3N5O
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SMILES
N[C@H](CC1)C[C@H]1N2C=NC(C3=CC=C(C(F)(F)F)C=C3)=C2C4=NC(OC5=CC=CC(C6CC6)=C5)=NC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD4 D1-IN-3 Related Classifications
HY-180831 Related Classifications
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