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Cat. No.: HY-17628S

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Cefiderocol-d₈

Name: Cefiderocol-d8
Brand: MedChemExpress
SKU: HY-17628S
Availability: PreOrder

(Synonyms: S-649266-d₈)

Cefiderocol-d₈ (S-649266-d₈) is the deuterated-labeled Cefiderocol (HY-17628). Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC₅₀s of 2 μg/mL or less.

For research use only. We do not sell to patients.

Formula: C₃₀H₂₆D₈ClN₇O₁₀S₂
Molecular Weight:760.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cefiderocol-d₈ Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

MIC50: <2 μg/mL (Gram-negative bacteria)^[1]

All Antibiotic Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 1225208-94-5
Molecular Weight 760.26
Formula C₃₀H₂₆D₈ClN₇O₁₀S₂
SMILES

O=C(C(N12)=C(C[N+]3(CCNC(C4=CC=C(O)C(O)=C4Cl)=O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C3([2H])[2H])CS[C@]2([H])[C@H](NC(/C(C5=CSC(N)=N5)=N\OC(C)(C(O)=O)C)=O)C1=O)[O-]
Synonyms

S-649266-d₈
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ito A, et al. In Vitro Antibacterial Properties of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacteria. Antimicrob Agents Chemother. 2017 Dec 21;62(1). [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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Cefiderocol-d8

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Cefiderocol-d8 Related Classifications

HY-17628S Related Classifications

Bioz

Cefiderocol-d₈

Cefiderocol-d₈ Related Classifications