CP-220629
CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg).
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- CAS No.: 162141-96-0
- Formule: C20H25N3O
- Masse moléculaire:323.43
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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PDE4 0.44 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | EC50 |
0.33 μM
Compound: 22
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Arbitary maximal response for cAMP elevation from baseline level was evaluated in Human U-937 cells
Arbitary maximal response for cAMP elevation from baseline level was evaluated in Human U-937 cells
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[PMID: 9632360] |
Chemical Information
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CAS No. 162141-96-0
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Masse moléculaire 323.43
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Formule C20H25N3O
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SMILES
O=C1C(N(C2CCCC2)N=C3CC)=C3CCN1C4=CC=CC=C4C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CP-220629 Related Classifications
HY-129785 Related Classifications
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