DPP8/9-IN-2
DPP8/9-IN-2 (Compound 21) is a DPP8/9 inhibitor with IC50 values of 0.22 nM and 3 nM, respectively, and Ki values of 2.9 nM and 6 nM, respectively . DPP8/9-IN-2 has certain cardiotoxicity, with IC50 values of 0.7 μM, 29.0 μM and 27.7 μM for hERG potassium channel, Nav1.5 sodium channel and Cav1.2 calcium channel, respectively. DPP8/9-IN-2 can be used in the research of diseases such as tumors.
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- CAS No.: 3109603-86-0
- Formule: C30H30F3N3O2
- Masse moléculaire:521.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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DPP-8 0.22 nM (IC50) |
DPP-9 3 nM (IC50) |
Nav1.5 29.0 μM (IC50) |
DPP-8 2.9 nM (Ki) |
DPP-9 6 nM (Ki) |
Chemical Information
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CAS No. 3109603-86-0
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Masse moléculaire 521.57
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Formule C30H30F3N3O2
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SMILES
O=C(N1CC2=C(C=C(F)C=C2)C1)[C@@H](N)CC(N3CCC(C(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DPP8/9-IN-2 Related Classifications
HY-175226 Related Classifications
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