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Cat. No.: HY-169184

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GDC-9918

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor.

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CAS No.: 2570375-06-1
Formule: C₂₀H₁₈F₂N₆O₅S
Masse moléculaire:492.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

GDC-9918 Chemical Structure

CAS No.: 2570375-06-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
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Chemical Information
Pureté et documentation
Références
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Activité biologique

Description

GDC-9918 (compund GDC-9918) is a Janus kinase inhibitor^[1].

IC₅₀ & Target

Janus^[1]

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Chemical Information

CAS No. 2570375-06-1
Masse moléculaire 492.46
Formule C₂₀H₁₈F₂N₆O₅S
SMILES

O=C(C1=C2N=CC=CN2N=C1)NC3=CN(C)N=C3C4=CC(S(=O)(CCO)=O)=CC=C4OC(F)F
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Dalton D M, et al. Development of a Robust Pd-Catalyzed C–S Coupling for the Synthesis of Janus Kinase Inhibitor GDC-9918[J]. Organic Process Research & Development, 2024, 28(10): 3858-3870.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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GDC-9918

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Activité biologique

Description

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Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

GDC-9918 Related Classifications

HY-169184 Related Classifications

Bioz

Keywords

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