JNJ627
JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis).
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- Formule: C29H38N4O3S
- Masse moléculaire:522.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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IL-17A |
Chemical Information
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Masse moléculaire 522.70
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Formule C29H38N4O3S
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SMILES
CC1(SCCN[C@H]1C(NCC2=CC=CC(C(N[C@@H](C3CCCCC3)C(NC4=CC=CC=C4)=O)=O)=C2)=O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JNJ627 Related Classifications
HY-178714 Related Classifications
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