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Cat. No.: HY-116610

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L 748780

L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC₅₀ values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively.

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CAS No.: 168086-64-4
Formule: C₁₉H₁₄Cl₃NO₄
Masse moléculaire:426.68

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

L 748780 Chemical Structure

CAS No.: 168086-64-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC₅₀ values of 0.5 μM and ＞ 100 μM for COX-2 and COX-1, respectively^[1].

IC₅₀ & Target

COX-2

0.5 μM (IC₅₀)

COX-1

> 100 μM (IC₅₀)

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Chemical Information

CAS No. 168086-64-4
Masse moléculaire 426.68
Formule C₁₉H₁₄Cl₃NO₄
SMILES

O=C(CC1=C(C)N(C(C2=C(Cl)C=C(Cl)C=C2Cl)=O)C3=C1C=C(C=C3)OC)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lau CK, et al. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors. Adv Exp Med Biol. 1997;407:73-8. PMID: 9321934. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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L 748780

Voir tous les produits spécifiques à Isoform COX

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

L 748780 Related Classifications

HY-116610 Related Classifications