L-764406
L-764406 is a non-thiazolidinedione (TZD)-type PPARg nuclear receptor ligand with high affinity. L-764406 has significant binding ability to PPARg (IC50=70 nM). L-764406 exhibited partial agonist activity and induced expression of the adipocyte-specific gene aP2 in chimeric receptors expressing the PPARg LBD and the corresponding reporter gene, as well as in 3T3-L1 cells. In contrast, L-764406 showed no activity in cells transfected with chimeric receptors containing PPARa or PPARd LBDs.
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- CAS No.: 227002-04-2
- Formule: C15H11ClN2O2S
- Masse moléculaire:318.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
PPARg Nuclear Receptor[1]
Chemical Information
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CAS No. 227002-04-2
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Masse moléculaire 318.78
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Formule C15H11ClN2O2S
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SMILES
O=S(CC1=NC2=CC=CC=C2N=C1Cl)(C3=CC=CC=C3)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-764406 Related Classifications
HY-121579 Related Classifications
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