PDE4-IN-4
PDE4-IN-4 is a dual M3 (pIC50 = 10.2) antagonist-PDE4 (pIC50 = 8.8) inhibitor for the inhaled research of pulmonary diseases.
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- CAS No.: 1793069-00-7
- Formule: C36H37Cl2N3O7S
- Masse moléculaire:726.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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PDE4 |
mAChR3 |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Eosinophil | ED50 |
30 nmol/Kg
Compound: 92a
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Anti-inflammatory activity against OVA-sensitized Brown-Norway rat airway inflammation model assessed as inhibition of OVA-induced eosinophil influx administered IT(Intratracheal) 2 hrs prior to OVA challenge
Anti-inflammatory activity against OVA-sensitized Brown-Norway rat airway inflammation model assessed as inhibition of OVA-induced eosinophil influx administered IT(Intratracheal) 2 hrs prior to OVA challenge
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[PMID: 37561958] |
Chemical Information
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CAS No. 1793069-00-7
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Masse moléculaire 726.67
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Formule C36H37Cl2N3O7S
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SMILES
O=C(C1=CC=C(CN[C@H](C2=CC=CC=C2)C(O[C@H]3CN4CCC3CC4)=O)S1)O[C@H](C5=CC=C(OC)C(OC)=C5)CC6=C(Cl)C=[N+]([O-])C=C6Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE4-IN-4 Related Classifications
HY-115871 Related Classifications
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