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Cat. No.: HY-160418

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PI3K-IN-51

PI3K-IN-51 is a PI3K inhibitor with IC₅₀ values <500 nM for p120γ and p110δ/p85α (WO2016204429A1; Example 10).

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CAS No.: 2055765-77-8
Formule: C₂₄H₁₇Cl₂N₅O₂
Masse moléculaire:478.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

PI3K-IN-51 Chemical Structure

CAS No.: 2055765-77-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

PI3K-IN-51 is a PI3K inhibitor with IC₅₀ values <500 nM for p120γ and p110δ/p85α (WO2016204429A1; Example 10)^[1].

Voir tous les produits spécifiques à Isoform PI3K :

Chemical Information

CAS No. 2055765-77-8
Masse moléculaire 478.33
Formule C₂₄H₁₇Cl₂N₅O₂
SMILES

O=C1C=CN=C(NC=N2)C1=C2N[C@H](C(N3C4=CC=CC=C4)=C(Cl)C5=CC=CC(Cl)=C5C3=O)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Heteroaryl derivative or pharmaceutically acceptable salt thereof, preparation method therefor, and pharmaceutical composition for preventing or treating diseases associated with pi3 kinases, containing same as active ingredient. Korea, WO2016204429A1. 2016-12-22.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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