ProINDY
Based on 1 Customer Validation
ProINDY, a prodrug of INDY (HY-108476), is a DYRK1A and DYRK1B inhibitor. ProINDY effectively recovers Xenopus embryos from head malformation induced by Dyrk1A overexpression.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 719277-30-2
- Formule: C14H15NO3S
- Masse moléculaire:277.34
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
In the cultured cells overexpressing Dyrk1A or xDyrk1A, ProINDY inhibits the phosphorylation of Thr212 of the tau-protein. ProINDY also rescues the NFAT pathway in Dyrk1A-overexpressing cells, confirming the identical Dyrk1A-inhibitory effect[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 719277-30-2
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Appearance Solid
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Masse moléculaire 277.34
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Formule C14H15NO3S
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SMILES
CC(/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ProINDY Related Classifications
HY-108475 Related Classifications
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