SSZ
Based on 1 publication(s) in Google Scholar
SSZ is a multi-target inhibitor, which targets multiple pathological mechanisms of Alzheimer's disease (AD). SSZ targets acetylcholinesterase, butyrylcholinesterase, β-site amyloid precursor protein cleavage enzyme 1 (BACE1), and γ-secretase. SSZ ameliorates Alzheimer’s diseases and exhibits neuroprotective effect in mice.
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- Pureté: 98.13%
- CAS No.: 1262287-23-9
- Formule: C18H19ClN4
- Masse moléculaire:326.82
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) SSZ
More
Activité biologique
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1262287-23-9
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Appearance Solid
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Masse moléculaire 326.82
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Formule C18H19ClN4
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Color Off-white to light yellow
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SMILES
ClC1=CC(C2=CNC3=C2C=CC=N3)=CC(NC4CCCCC4)=N1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Immunol
Radiotherapy enhances anticancer CD8 T cell responses by cGAMP transfer through LRRC8A/C volume-regulated anion channels. [Abstract]2025 Jun 27;10(108):eadn1630. PMID: 40577443
Solvant et solubilité
DMSO : 50 mg/mL (152.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0598 mL | 15.2989 mL | 30.5979 mL | 76.4947 mL |
| 5 mM | 0.6120 mL | 3.0598 mL | 6.1196 mL | 15.2989 mL | |
| 10 mM | 0.3060 mL | 1.5299 mL | 3.0598 mL | 7.6495 mL | |
| 15 mM | 0.2040 mL | 1.0199 mL | 2.0399 mL | 5.0996 mL | |
| 20 mM | 0.1530 mL | 0.7649 mL | 1.5299 mL | 3.8247 mL | |
| 25 mM | 0.1224 mL | 0.6120 mL | 1.2239 mL | 3.0598 mL | |
| 30 mM | 0.1020 mL | 0.5100 mL | 1.0199 mL | 2.5498 mL | |
| 40 mM | 0.0765 mL | 0.3825 mL | 0.7649 mL | 1.9124 mL | |
| 50 mM | 0.0612 mL | 0.3060 mL | 0.6120 mL | 1.5299 mL | |
| 60 mM | 0.0510 mL | 0.2550 mL | 0.5100 mL | 1.2749 mL | |
| 80 mM | 0.0382 mL | 0.1912 mL | 0.3825 mL | 0.9562 mL | |
| 100 mM | 0.0306 mL | 0.1530 mL | 0.3060 mL | 0.7649 mL |
SSZ Related Classifications
HY-163885 Related Classifications
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