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Cat. No.: HY-176488

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Y-99

Y-99 is a PORCN inhibitor with an IC₅₀ of 155.4 nM against the Wnt/β-catenin signaling pathway. Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc.

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CAS No.: 2034334-74-0
Formule: C₁₈H₁₇F₂N₅O₃
Masse moléculaire:389.36

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Y-99 Chemical Structure

CAS No.: 2034334-74-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Y-99 is a PORCN inhibitor with an IC₅₀ of 155.4 nM against the Wnt/β-catenin signaling pathway. Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc^[1].

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Chemical Information

CAS No. 2034334-74-0
Masse moléculaire 389.36
Formule C₁₈H₁₇F₂N₅O₃
SMILES

O=C(NCC1=NC(C2CCC(F)(F)CC2)=NO1)C3=NOC(C4=CC=CN=C4)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yang X, et al. Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening. ACS Chem Biol. 2025 Jun 20;20(6):1319-1332. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
Références

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Y-99

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