1033735-94-2
1033735-94-2
Chemical Structure
GNE-493
- CAS No.: 1033735-94-2
- Formula:C17H20N6O2S
- Molecular Weight:372.44
IUPAC Name: 2-(2-(2-aminopyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol
InChIKey: LEXMMFPAPDGYGZ-UHFFFAOYSA-N
SMILES: OC(C)(C)C1=CC2=C(S1)C(N3CCOCC3)=NC(C4=CN=C(N)N=C4)=N2
Biological Activity: GNE-493 is a potent, selective, and orally available dual pan-PI3-kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE-493 | 99.81% | GNE-493 is a potent, selective, and orally available dual pan-PI3-kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. | ||||||||||||||||||||
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GNE-493 (Standard) | GNE-493 (Standard) is the analytical standard of GNE-493 (HY-10811). This product is intended for research and analytical applications. GNE-493 is a potent, selective, and orally available dual pan-PI3-Kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR. | |||||||||||||||||||||
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Keywords
