GNE-493 (Standard)
GNE-493 (Standard) is the analytical standard of GNE-493 (HY-10811). This product is intended for research and analytical applications. GNE-493 is a potent, selective, and orally available dual pan-PI3-Kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.
For research use only. We do not sell to patients.
- CAS No.: 1033735-94-2
- Formula: C17H20N6O2S
- Molecular Weight:372.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 3.4 nM (PI3Kα), 12 nM (PI3Kβ), 16 nM (PI3Kδ), 16 nM (PI3Kγ), 32 nM (mTOR)[1]
Chemical Information
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CAS No. 1033735-94-2
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Molecular Weight 372.44
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Formula C17H20N6O2S
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SMILES
OC(C)(C)C1=CC2=C(S1)C(N3CCOCC3)=NC(C4=CN=C(N)N=C4)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)