1. Cell Cycle/DNA Damage
    PROTAC
  2. CDK
    Ligand for Target Protein for PROTAC
  3. CDK ligand for PROTAC hydrochloride

CDK ligand for PROTAC hydrochloride 

Cat. No.: HY-126534A Purity: 99.01%
Handling Instructions

CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. CDK ligand for PROTAC hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader.

For research use only. We do not sell to patients.

CDK ligand for PROTAC hydrochloride Chemical Structure

CDK ligand for PROTAC hydrochloride Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 409 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
25 mg USD 990 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of CDK ligand for PROTAC hydrochloride:

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Description

CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. CDK ligand for PROTAC hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1].

Molecular Weight

531.00

Formula

C₂₅H₂₉ClF₂N₈O

SMILES

FC(C=N1)=C(C2=CC(N(C(C)C)C(CO)=N3)=C3C(F)=C2)N=C1NC4=NC=C(C=C4)CN5CCNCC5.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (235.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8832 mL 9.4162 mL 18.8324 mL
5 mM 0.3766 mL 1.8832 mL 3.7665 mL
10 mM 0.1883 mL 0.9416 mL 1.8832 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

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Keywords:

CDK ligand for PROTACCDKLigand for Target Protein for PROTACCyclin dependent kinaseTarget Protein-binding MoietyligandantitumorCRBNdegraderPROTACInhibitorinhibitorinhibit

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Product name:
CDK ligand for PROTAC hydrochloride
Cat. No.:
HY-126534A
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