1. Apoptosis
  2. TNF Receptor
  3. Cenzestotug

Cenzestotug  (Synonyms: YH-002)

Cat. No.: HY-P991125 Purity: 99.447%
Technical Support

Cenzestotug is a monoclonal antibody targeting human tumor necrosis factor receptor superfamily member 4 (TNFRSF4). Cenzestotug activates relevant immune cells by binding to TNFRSF4, exerting immunostimulatory and antitumor activities. Cenzestotug is promising for research of cancer immunotherapy.

For research use only. We do not sell to patients.

CAS No. : 3014361-58-8

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Based on 1 publication(s) in Google Scholar

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Description

Cenzestotug is a monoclonal antibody targeting human tumor necrosis factor receptor superfamily member 4 (TNFRSF4). Cenzestotug activates relevant immune cells by binding to TNFRSF4, exerting immunostimulatory and antitumor activities. Cenzestotug is promising for research of cancer immunotherapy[1].

Isotype

Human IgG1 kappa

Recommend Isotype Controls
Species Reactivity

Human

IC50 & Target

TNFRSF4/OX40/CD134

Clinical Trial
Gene ID

7293  [NCBI]

Accession
Application

ELISA, FACS, Functional assay

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Cenzestotug]

Shipping

Shipping with dry ice.

Formulation

Please refer to the lot-specific COA for specific buffer information.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa
Biological Activity
  • Immobilized HY-P7394 OX40/TNFRSF4 Protein, Human (HEK293, His) can bind Cenzestotug. The EC50 for this effect is 10.2 ng/mL.
Purity & Documentation
References
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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cenzestotug
Cat. No.:
HY-P991125
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