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Certolizumab pegol

(Synonyms: Certolizumab; CDP870)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Certolizumab pegol (Certolizumab) is a recombinant, polyethylene glycosylated, antigen-binding fragment of a humanized monoclonal antibody that selectively targets and neutralizes tumour necrosis factor-α (TNF-α). Certolizumab pegol can be used for rheumatoid arthritis and Crohn disease research.

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  • Pureté: 99.00%
  • CAS No.: 428863-50-7
  • Masse moléculaire:91 kDa
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Certolizumab pegol
  • Experimental Validation Results for Certolizumab pegol
  • Experimental Validation Results for Certolizumab pegol
  • Certolizumab pegol Chemical Structure
    Certolizumab pegol Chemical Structure
CAS No.: 428863-50-7
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609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Fab'-G1-kappa

  • 1/16

    Immobilized TNF-alpha/TNFSF2 Protein, Human (HY-P7058) can bind Certolizumab pegol. The EC50 for this effect is 238 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 RAW264.7 cells treated with 1µg/mL LPS for 24h with Certolizumab pegol (HY-P9953, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Certolizumab pegol Chemical Structure
    1/16
  • Certolizumab pegol
  • Immobilized TNF-alpha/TNFSF2 Protein, Human (HY-P7058) can bind Certolizumab pegol. The EC50 for this effect is 238 ng/mL.
  • Flow cytometric analysis of 1.5X106 RAW264.7 cells treated with 1µg/mL LPS for 24h with Certolizumab pegol (HY-P9953, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab'-G1-kappa