p38α-IN-13
p38α-IN-13 is p38α MAPK, BChE and AChE inhibitor with IC50 values of 5.79, 16.24, 51.8 µM for p38α MAP, hBChE, hAChE, respectively. p38α-IN-13 has the potential for the research of Alzheimer’s disease.
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- CAS. Nr.: 3077831-12-7
- Formel: C22H26F2N4O2
- Molecular Weight:416.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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p38α MAPK 5.79 μM (IC50) |
hBCHE 16.24 μM (IC50) |
hAChE 51.8 μM (IC50) |
p38α-IN-13 (5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-2-isobutyl-2H-indazole-6-carboxamide) is a p38α MAPK, BChE and AChE inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 3077831-12-7
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Molecular Weight 416.46
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Formel C22H26F2N4O2
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SMILES
O=C(C1=CC2=NN(CC(C)C)C=C2C=C1OC3=CC=C(F)C=C3F)NCCN(C)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
p38α-IN-13 Related Classifications
HY-114422 Related Classifications
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