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Art. -Nr.: HY-167160

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AZ12099548

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization.

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CAS. Nr.: 790689-76-8
Formel: C₁₉H₂₀N₂O₃S
Molecular Weight:356.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZ12099548 Chemical Structure

CAS. Nr.: 790689-76-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

AZ12099548 is a TRPV1 antagonist. AZ12099548 inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization^[1].

IC₅₀ & Target^[1]

hTRPV1

Alle TRP Channel Isoform-spezifische Produkte anzeigen :

In Vitro

AZ12099548 (Compound AZ C) inhibits both Capsaicin (HY-10448)- and low pH-induced calcium mobilization in human TRPV1-expressing cells, with IC₅₀ values of 10 nM and 22 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 790689-76-8
Molecular Weight 356.44
Formel C₁₉H₂₀N₂O₃S
SMILES

O=C(NC=1C=CC=2SC(=NC2C1)CO)C3=CC=C(OC(C)(C)C)C=C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Cuypers E, et al. Transient receptor potential vanilloid 1 and xenobiotics. CNS Neurol Disord Drug Targets. 2008;7(2):159-171. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
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AZ12099548

Alle TRP Channel Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

AZ12099548 Related Classifications

HY-167160 Related Classifications