CG-3-246
CG-3-246 is a dual inhibitor of FLT3/BCL-2, with the Kds of 63 and 4.25 nM, respectibely. CG-3-246 plays an important role in acute myeloid leukemias research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C64H73ClN14O10S
- Molecular Weight:1265.87
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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Molecular Weight 1265.87
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Formel C64H73ClN14O10S
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SMILES
O=C(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC=C(N4CCN(C(CNC5=CC=C(S(=O)(NC(C6=CC=C(N7CCN(CC8=C(C9=CC=C(Cl)C=C9)CC(C)(C)CC8)CC7)C=C6OC%10=CN=C(NC=C%11)C%11=C%10)=O)=O)C=C5[N+]([O-])=O)=O)CC4)C(OC)=C3)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Christopher C Goodis, et al. The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN–GIL hybrid single-molecule inhibitors. Eur J Med Chem. 2024 Dec 22:285:117190. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CG-3-246 Related Classifications
HY-170689 Related Classifications
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