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Art. -Nr.: HY-N17777

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Cyclocarin A

Cyclocarin A is a triterpenoid compound that can be isolated from the leaves of Cyclocarya paliurus. Cyclocarin A shows only weak inhibitory activity against α-glucosidase, lipase, DPP-IV, and aldose reductase.

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CAS. Nr.: 1403937-45-0
Formel: C₃₁H₅₀O₄
Molecular Weight:486.73

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Cyclocarin A Chemical Structure

CAS. Nr.: 1403937-45-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]^[2]

DPP-4

α‑glucosidase

lipase

Aldose reductase

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Cellular Effect

Cell Line	Type	Value	Description	References
Cancer cell lines	IC50	10 μM	Cytotoxicity against several human cancer cell lines with IC50 > 10 µM. Cytotoxicity against several human cancer cell lines with IC50 > 10 µM.	22161740

In Vitro

Carbohydrate MetabolismLipid MetabolismProtein/Amino Acid Metabolism

Carbohydrate Metabolism

Cyclocarin A (40 µM) shows weak α-glucosidase inhibition (2.9%)^[1].
Cyclocarin A (10 µM) shows weak aldose reductase inhibition (9.1%)^[1].

Lipid Metabolism

Cyclocarin A (5 µM) shows weak lipase inhibition (8.4%)^[1].

Protein/Amino Acid Metabolism

Cyclocarin A (10 µM) shows weak DPP-IV inhibition (15.7%)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1403937-45-0
Molecular Weight 486.73
Formel C₃₁H₅₀O₄
SMILES

C[C@]12[C@]3([C@@](C[C@H]([C@]1([H])[C@@](CC2)([H])[C@@](C)(O)C/C=C/C(C)=C)O)([H])[C@](C)([C@@H](CC3)C(C)=C)CCC(OC)=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Li S, et al. New triterpenoids from the leaves of Cyclocarya paliurus. Planta Med. 2012 Feb;78(3):290-6. [Content Brief]

[2]. Chen YJ, et al. Seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus. Phytochemistry. 2018 Jan;145:85-92.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Cyclocarin A

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