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Art. -Nr.: HY-105237

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Eesperamicin A1

Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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CAS. Nr.: 99674-26-7
Formel: C₅₉H₈₀N₄O₂₂S₄
Molecular Weight:1325.54

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

Eesperamicin A1 Chemical Structure

CAS. Nr.: 99674-26-7

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Biologische Aktivität

Beschreibung

Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor^[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	1.0 x 10^-12M Compound: Esperamicin A1	Cytotoxicity against HCT116 human colon tumor cell line Cytotoxicity against HCT116 human colon tumor cell line	10.1016/0960-894X(95)00163-N

Chemical Information

CAS. Nr. 99674-26-7
Molecular Weight 1325.54
Formel C₅₉H₈₀N₄O₂₂S₄
SMILES

CSSSC/C=C1C2=C(C([C@@H](O[C@@]3([H])C[C@@H]([C@H](O)[C@H](C)O3)OC(C4=C(C=C(OC)C(OC)=C4)NC(C(OC)=C)=O)=O)[C@]\1(C#C/C=C\C#C[C@@H]2O[C@@]5([H])[C@@H]([C@H]([C@H](NO[C@H]6C[C@@H]([C@H](SC)[C@@H](C)O6)O)[C@@H](C)O5)O)O[C@@]7([H])C[C@@H]([C@@H](NC(C)C)CO7)OC)O)=O)NC(OC)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115(26), 12340–12345.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Eesperamicin A1

Alle Antibiotic Isoform-spezifische Produkte anzeigen

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Biologische Aktivität

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Eesperamicin A1 Related Classifications

HY-105237 Related Classifications