F7H
Based on 2 publication(s) in Google Scholar
F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.95%
- CAS. Nr.: 897109-93-2
- Formel: C24H18FN3O2S2
- Molecular Weight:463.55
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Publications Citing Use of MedChemExpress (MCE) F7H
More
Biologische Aktivität
IC50: 1.25 μM (Frizzled receptor, FZD7)[1]
Chemical Information
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CAS. Nr. 897109-93-2
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Appearance Solid
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Molecular Weight 463.55
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Formel C24H18FN3O2S2
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Color White to off-white
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SMILES
O=C(C1=CC=C(C=C1)F)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Free Radic Biol Med
N6-methyladenosine regulated FZD7 inhibits ferroptosis in endometriosis via β-catenin/SLC7A11 pathway. [Abstract]2025 Nov 13:243:54-66. PMID: 41241001 -
Sci Rep
Identification of FZD7 as a potential ferroptosis-related diagnostic gene in endometriosis by bioinformatics analysis. [Abstract]2025 Feb 28;15(1):7172. PMID: 40021920
Lösungsmittel & Löslichkeit
DMSO : 125 mg/mL (269.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1573 mL | 10.7863 mL | 21.5726 mL | 53.9316 mL |
| 5 mM | 0.4315 mL | 2.1573 mL | 4.3145 mL | 10.7863 mL | |
| 10 mM | 0.2157 mL | 1.0786 mL | 2.1573 mL | 5.3932 mL | |
| 15 mM | 0.1438 mL | 0.7191 mL | 1.4382 mL | 3.5954 mL | |
| 20 mM | 0.1079 mL | 0.5393 mL | 1.0786 mL | 2.6966 mL | |
| 25 mM | 0.0863 mL | 0.4315 mL | 0.8629 mL | 2.1573 mL | |
| 30 mM | 0.0719 mL | 0.3595 mL | 0.7191 mL | 1.7977 mL | |
| 40 mM | 0.0539 mL | 0.2697 mL | 0.5393 mL | 1.3483 mL | |
| 50 mM | 0.0431 mL | 0.2157 mL | 0.4315 mL | 1.0786 mL | |
| 60 mM | 0.0360 mL | 0.1798 mL | 0.3595 mL | 0.8989 mL | |
| 80 mM | 0.0270 mL | 0.1348 mL | 0.2697 mL | 0.6741 mL | |
| 100 mM | 0.0216 mL | 0.1079 mL | 0.2157 mL | 0.5393 mL |
F7H Related Classifications
HY-156095 Related Classifications
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