Isethionic acid sodium
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Isethionic acid sodium salt (2-Hydroxyethanesulfonic acid sodium; Sodium isethionate) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid sodium salt forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid sodium salt enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis.
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- Reinheit : 99.88%
- CAS. Nr.: 1562-00-1
- Formel: C2H5NaO4S
- Molecular Weight:148.11
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
Isethionic acid sodium salt inhibits the attachment of Balanus amphitrite cyprids in a concentration-dependent manner in an in vitro seawater bioassay system, and larval mortality increases at concentrations above 0.01 mg/mL[1].
Isethionic acid sodium salt can undergo an enzymatic reaction with bile acids under the catalysis of rat liver microsomal preparations to form choyl-ethanesulfonic acid through ester bonds[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
Isethionic acid sodium salt has a higher distribution in cardiac tissue than in muscle at the injection site[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1562-00-1
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Appearance Solid
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Molecular Weight 148.11
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Formel C2H5NaO4S
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Color White to off-white
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SMILES
OCCS(=O)(O[Na])=O
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Synonyms
2-Hydroxyethanesulfonic acid sodium; Sodium isethionate
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 100 mg/mL (675.17 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Hellio C, et al. Isethionic acid and floridoside isolated from the red alga, Grateloupia turuturu, inhibit settlement of Balanus amphitrite cyprid larvae. Biofouling. 2004 Jun;20(3):139-45. [Content Brief]
[3]. Lombardini JB. Enzymatic formation of a cholic acid derivative of isethionic acid. Biochem Pharmacol. 1976 Mar 15;25(6):717-21. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.7517 mL | 33.7587 mL | 67.5174 mL | 168.7935 mL |
| 5 mM | 1.3503 mL | 6.7517 mL | 13.5035 mL | 33.7587 mL | |
| 10 mM | 0.6752 mL | 3.3759 mL | 6.7517 mL | 16.8793 mL | |
| 15 mM | 0.4501 mL | 2.2506 mL | 4.5012 mL | 11.2529 mL | |
| 20 mM | 0.3376 mL | 1.6879 mL | 3.3759 mL | 8.4397 mL | |
| 25 mM | 0.2701 mL | 1.3503 mL | 2.7007 mL | 6.7517 mL | |
| 30 mM | 0.2251 mL | 1.1253 mL | 2.2506 mL | 5.6264 mL | |
| 40 mM | 0.1688 mL | 0.8440 mL | 1.6879 mL | 4.2198 mL | |
| 50 mM | 0.1350 mL | 0.6752 mL | 1.3503 mL | 3.3759 mL | |
| 60 mM | 0.1125 mL | 0.5626 mL | 1.1253 mL | 2.8132 mL | |
| 80 mM | 0.0844 mL | 0.4220 mL | 0.8440 mL | 2.1099 mL | |
| 100 mM | 0.0675 mL | 0.3376 mL | 0.6752 mL | 1.6879 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Isethionic acid sodium Related Classifications
HY-Y1173 Related Classifications
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Keywords
- Isethionic acid
- 1562-00-1
- 2-Hydroxyethanesulfonic acid
- Sodium
- Endogenous Metabolite
- Parasite
- Balanus amphitrite cyprid larvae
- rat liver microsomal preparations
- Balanus amphitrite nauplius larvae
- Grateloupia turuturu
- cholic acid
- giant squid axoplasm
- taurine
- white mice
- rats
- mammalian tissues
- Inhibitor
- inhibitor
- inhibit