ML-B01
ML-B01 is the orally active inhibitor for Akt and PKA with the IC50 of 2 nM and 136 nM. ML-B01 exhibits good ability to penetrate the blood-brain barrier (BBB) in the mouse brain.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C24H31Cl2N5O
- Molecular Weight:476.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
IC50: 2 nM (Akt), 136 nM (PKA)
Chemical Information
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Molecular Weight 476.44
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Formel C24H31Cl2N5O
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SMILES
O=C(N1CCN(C2=C([C@H](C)C[C@H]3Cl)C3=NC=N2)CC1)[C@@H](C4=CC=C(Cl)C=C4)CNC(C)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)