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Art. -Nr.: HY-123391

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PD 127443

PD 127443 is an inhibitor of 5-lipoxygenase and cyclooxygenase. PD 127443 has anti-inflammatory activity.

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CAS. Nr.: 121502-05-4
Formel: C₂₀H₂₈N₂O
Molecular Weight:312.45

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

PD 127443 Chemical Structure

CAS. Nr.: 121502-05-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PD 127443 is an inhibitor of 5-lipoxygenase and cyclooxygenase. PD 127443 has anti-inflammatory activity^[1].

Alle Lipoxygenase Isoform-spezifische Produkte anzeigen :

Alle COX Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	0.9 μM Compound: 33	Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assay Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assay	[PMID: 1847426]
RBL-1	IC₅₀	3 μM Compound: 33	Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells	[PMID: 1847426]

Chemical Information

CAS. Nr. 121502-05-4
Molecular Weight 312.45
Formel C₂₀H₂₈N₂O
SMILES

OC1=C(C=C(C=C1C(C)(C)C)/C=C/C2=NNC(C)=C2)C(C)(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Schrier DJ, et al. The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase. Agents Actions. 1989 Jun;27(3-4):391-4. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Reinheit & Dokumentation
Verweise

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PD 127443

Alle Lipoxygenase Isoform-spezifische Produkte anzeigen

Alle COX Isoform-spezifische Produkte anzeigen