Physalin H
Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively.
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- CAS. Nr.: 70241-09-7
- Formel: C28H31ClO10
- Molecular Weight:562.99
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 70241-09-7
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Molecular Weight 562.99
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Formel C28H31ClO10
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SMILES
C[C@@]([C@H](OC1=O)C2)(OC3=O)[C@](O[C@@]45C6=O)([C@]3(CC[C@@]([C@]([C@@]7(CC=C8)Cl)(C8=O)C)([H])[C@@]4([H])C[C@H]7O)O)[C@@]6([H])[C@]2([C@@]1([H])CO5)C
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Physalin H Related Classifications
HY-N8270 Related Classifications
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