PT-S58
PT-S58, a GSK0660 derivative, is a PPARβ/δ full antagonist with an IC50 value of 98 nM. PT-S58 inhibits the agonist-induced transcriptional activity of PPARβ/δ in vitro.
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- CAS. Nr.: 1356497-92-1
- Formel: C17H22N2O5S2
- Molecular Weight:398.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
PPARβ/δ 98 nM (IC50) |
Chemical Information
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CAS. Nr. 1356497-92-1
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Molecular Weight 398.50
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Formel C17H22N2O5S2
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SMILES
O=C(C1=C(S(=O)(NC2=CC=C(NC(C)(C)C)C=C2OC)=O)C=CS1)OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Dual Luciferin reporter gene assay
Luciferin reporter gene assay is a reporting system to detect the activity of Firefly Luciferase using luciferin as a substrate, which is often used in the research of miRNA target gene verification and promoter transcriptive activity regulation. Dual luciferase usually refers to Firefly luciferase and Renilla luciferase.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)