MMAF-methyl ester
MMAF-methyl ester is a methylated derivative of the tubulin inhibitor MMAF (HY-15579), and serves as a pharmaceutical intermediate for the development of antibody-drug conjugates (ADCs) and small-molecule drug conjugates (SMDCs).
For research use only. We do not sell to patients.
- CAS No.: 2353409-70-6
- Formula: C40H67N5O8
- Molecular Weight:745.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MMAF is a potent tubulin polymerization inhibitor that is widely used as the cytotoxic component of antibody-drug conjugates (ADCs), such as Vorsetuzumab mafodotin (HY-P99334).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2353409-70-6
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Molecular Weight 745.99
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Formula C40H67N5O8
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SMILES
COC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(CC(OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](NC)C(C)C)=O)=O)=O)OC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MMAF-methyl ester Related Classifications
HY-W190923 Related Classifications
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