Thio-ITP
Thio-ITP (6-Thioinosine 5′-triphosphate) is an RNA polymerase activity competitive inhibitor. Thio-ITP has a high apparent affinity for the polymerases (RNA polymerase I Ki: 40.9 μM; RNA polymerase II Ki: 38.0 μM).
For research use only. We do not sell to patients.
- CAS No.: 27652-34-2
- Formula: C10H15N4O13P3S
- Molecular Weight:524.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
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RNA Polymerase |
RNA polymerase I 40.9±11.0 μM (Ki) |
RNA polymerase II 38.0±6.47 μM (Ki) |
Thio-ITP inhibits both endogenous and exogenous DNA-directed RNA synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 27652-34-2
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Molecular Weight 524.23
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Formula C10H15N4O13P3S
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SMILES
SC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O3
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Synonyms
6-Thioinosine 5′-triphosphate; 6-Mercaptopurine-riboside-5'-triphosphate; 6-Thio-ITP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thio-ITP Related Classifications
HY-115755 Related Classifications
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