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Cat. No.: HY-N20636

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7α-Morroniside

7α-Morroniside is a STAT3 promoter inhibitor. 7α-Morroniside inhibits IL-6-induced STAT3 promoter activity in hepatocellular carcinoma cells. 7α-Morroniside can be used for the research of inflammation-related diseases.

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CAS No.: 61849-88-5
Formule: C₁₇H₂₆O₁₁
Masse moléculaire:406.38

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

7α-Morroniside Chemical Structure

CAS No.: 61849-88-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

STAT3

Voir tous les produits spécifiques à Isoform STAT :

In Vitro

7α-Morroniside (Compound 22) (7 μM; 1 h pre-incubation + 6 h co-incubation with IL-6) potently inhibits IL-6-induced STAT3 promoter activity in HepG2 cells, with an IC₅₀ of 7 μM, and shows no cytotoxicity at effective concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 61849-88-5
Masse moléculaire 406.38
Formule C₁₇H₂₆O₁₁
SMILES

COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])C[C@H](O[C@H]2C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Ye XS, et al.. Cornusides A-O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis. Journal of natural products. 2017 Dec 22;80(12):3103-3111. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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7α-Morroniside

Voir tous les produits spécifiques à Isoform STAT

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

7α-Morroniside Related Classifications

HY-N20636 Related Classifications