Capricostatin A
Capricostatin A is a glycosylated heteromeric depsipeptide and Antibacterial agent. Capricostatin A is present in the fungus Austroacremonium gemini MST-FP2131. Capricostatin A inhibits the growth of Gram-positive bacteria, including Bacillus subtilis, Staphylococcus aureus, and MRSA. Capricostatin A exhibits no antifungal activity against Saccharomyces cerevisiae and no cytotoxicity against mammalian cells. Capricostatin A can be used in the research of bacterial infections caused by Bacillus subtilis and Staphylococcus aureus.
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- Formule: C36H50O12
- Masse moléculaire:674.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
[1]|
Fungal Metabolite |
In Vitro
Capricostatin A inhibits the growth of Bacillus subtilis, Staphylococcus aureus, and Methicillin (HY-121544)-resistant S. aureus with MIC values of 1.6 μg mL−1, 3.1 μg mL−1, and 6.3 μg mL−1, respectively, but does not inhibit Saccharomyces cerevisiae, mouse myeloma NS-1 cells, or neonatal foreskin fibroblast cells at the tested concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 674.78
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Formule C36H50O12
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SMILES
OC[C@@H](O[C@H]1OC2=CC(CCCCCCC/C=C\CCCCCC)=C(C(OC(C=C3C)=CC(O)=C3C(O)=O)=O)C(O)=C2)[C@@H]([C@@H]([C@H]1O)O)O
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Structure Classification
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Initial Source
Austroacremonium gemini
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Capricostatin A Related Classifications
HY-N20645 Related Classifications
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Keywords
- Capricostatin A
- Bacterial
- Endogenous Metabolite
- Antibiotic
- mammalian cells
- neonatal foreskin fibroblast cells
- Bacillus subtilis
- Saccharomyces cerevisiae
- methicillin-resistant S. aureus (MRSA)
- bacterial infections
- mouse myeloma NS-1 cells
- Staphylococcus aureus
- Gram-positive bacteria
- Austroacremonium gemini MST-FP2131
- Inhibitor
- inhibitor
- inhibit