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Cat. No.: HY-182974

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DCAF1 binder 3

DCAF1 binder 3 is a DCAF1 binder and an E3 ligase ligand. DCAF1 binder 3 can be used to synthesize PROTAC SAMHD1 Degrader-1 (HY-182970).

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CAS No.: 3033533-52-4
Formule: C₁₉H₂₅FN₆
Masse moléculaire:356.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

DCAF1 binder 3 Chemical Structure

CAS No.: 3033533-52-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

DCAF1 binder 3 is a DCAF1 binder and an E3 ligase ligand. DCAF1 binder 3 can be used to synthesize PROTAC SAMHD1 Degrader-1 (HY-182970)^[1].

IC₅₀ & Target^[1]

DCAF1

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase :

In Vitro

DCAF1 binder 3 (Compound 19) DCAF1 binder 3 can be used to synthesize PROTAC SAMHD1 Degrader-1 (HY-182970)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3033533-52-4
Masse moléculaire 356.44
Formule C₁₉H₂₅FN₆
SMILES

FC1=CC=CC(N2CCC[C@@H](NC3=NC=NC(N4CCNCC4)=C3)C2)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Chen X, et al. Discovery and Evaluation of a PROTAC Degrader Targeting SAMHD1 for the Treatment of Pulmonary Fibrosis. J Med Chem. Published online April 3, 2026. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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DCAF1 binder 3

Voir tous les produits spécifiques à Isoform Ligands for E3 Ligase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DCAF1 binder 3 Related Classifications

HY-182974 Related Classifications