MAGEA12 - MAGE family member A12 Gene

Also Known as CT1.12; MAGE12

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4111

About MAGEA12

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:152,733,757-152,737,669 (from NCBI)

This gene has 3 transcripts (splice variants), 459 orthologues and 37 paralogues. Restricted expression toward testis (RPKM 1.8).

Summary

This gene is closely related to several Other genes clustered on chromosome X. These genes may be overexpressed in tumors. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq, Jun 2014]

MAGEA12 Products (3)

mRNA Protein Name
NM_001166386.3 NP_001159858.1 melanoma-associated antigen 12
NM_001166387.4 NP_001159859.1 melanoma-associated antigen 12
NM_005367.7 NP_005358.2 melanoma-associated antigen 12

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAGEA12 Protein Structure

MAGE_N

MAGE_N: Melanoma associated antigen family N terminal (4 - 97)

MAGE

MAGE: MAGE family (116 - 286)

  • 0
  • 100
  • 200
  • 300
  • 314 a.a.
Protein Preferred Names Protein Names

melanoma-associated antigen 12

  • MAGE12F antigen

MAGEA12 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
MAGEA12 P43365 NANOS2 Homo sapiens P60321
Validated Y2H
32296183
Intra
MAGEA12 P43365 NANOS2 Homo sapiens P60321
Y2H Array
25416956
Intra
MAGEA12 P43365 NANOS2 Homo sapiens P60321
Y2H Array
31515488
Intra
MAGEA12 P43365 FASTKD3 Homo sapiens Q14CZ7
Validated Y2H
25416956
Intra
MAGEA12 P43365 MTFR2 Homo sapiens Q6P444
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 MTFR2 Homo sapiens Q6P444
Y2H Array
25416956
Intra
MAGEA12 P43365 POLL Homo sapiens Q9UGP5-2
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 POLL Homo sapiens Q9UGP5-2
Validated Y2H
32296183
Intra
MAGEA12 P43365 POLL Homo sapiens Q9UGP5-2
Validated Y2H
25416956
Intra
MAGEA12 P43365 POLL Homo sapiens Q9UGP5-2
Y2H Array
25416956
Intra
MAGEA12 P43365 POU6F2 Homo sapiens P78424
Validated Y2H
32296183
Intra
MAGEA12 P43365 TBC1D19 Homo sapiens Q8N5T2
Y2H Array
25416956
Intra
MAGEA12 P43365 TBC1D19 Homo sapiens Q8N5T2
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 TCP11L1 Homo sapiens Q9NUJ3
Validated Y2H
32296183
Intra
MAGEA12 P43365 MTFR1L Homo sapiens Q9H019
Validated Y2H
25416956
Intra
MAGEA12 P43365 ZNF33B Homo sapiens Q06732
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 CLIP4 Homo sapiens Q8N3C7
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 CLIP4 Homo sapiens Q8N3C7
Validated Y2H
25416956
Intra
MAGEA12 P43365 CLIP4 Homo sapiens Q8N3C7
Validated Y2H
32296183
Intra
MAGEA12 P43365 CLIP4 Homo sapiens Q8N3C7
Y2H Array
25416956
Intra
MAGEA12 P43365 C16orf87 Homo sapiens Q6PH81
Validated Y2H
32296183
Intra
MAGEA12 P43365 C16orf87 Homo sapiens Q6PH81
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 C16orf87 Homo sapiens Q6PH81
Validated Y2H
25416956
Intra
MAGEA12 P43365 KANSL1 Homo sapiens Q7Z3B3
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 KANSL1 Homo sapiens Q7Z3B3
Validated Y2H
25416956
Intra
MAGEA12 P43365 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra
MAGEA12 P43365 HK2 Homo sapiens P52789
Validated Y2H
25416956
Intra
MAGEA12 P43365 HK2 Homo sapiens P52789
Y2H Array
25416956
Intra
MAGEA12 P43365 ABI3 Homo sapiens Q9P2A4
Y2H Array
25416956
Intra
MAGEA12 P43365 FNDC11 Homo sapiens Q9BVV2
Y2H Prey Pooling
25416956
Intra
MAGEA12 P43365 FNDC11 Homo sapiens Q9BVV2
Validated Y2H
25416956
Intra
MAGEA12 P43365 FNDC11 Homo sapiens Q9BVV2
Validated Y2H
32296183
Intra
MAGEA12 P43365 NPPA Homo sapiens P01160
Y2H Array
25416956
Intra
MAGEA12 P43365 NPPA Homo sapiens P01160
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P2269A MAIT-203 acetate 99.12% Unkown
HY-RS07966 MAGEA12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P2269 MAIT-203 / Unkown

Orthologs Information

Species Symbol Source ID
Others MAGEA12 NCBI