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Lusvertikimab

(Synonyms: OSE-127)
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Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research.

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  • Pureté: 99.41%
  • CAS No.: 2375835-91-7
  • Masse moléculaire:145.64 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Lusvertikimab
  • Experimental Validation Results for Lusvertikimab
  • Experimental Validation Results for Lusvertikimab
  • Lusvertikimab Chemical Structure
    Lusvertikimab Chemical Structure
CAS No.: 2375835-91-7
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609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human IL-7R alpha/CD127 Protein (ECD, His Tag) can bind Lusvertikimab. The EC50 for this effect is 3.8 ng/mL.

  • 1/16

    Flow Cytometry analysis of K562 cells labelling IL-7Ra/CD127 (red) with Lusvertikimab (anti-IL-7Ra/CD127) (HY-P99412). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.

  • Lusvertikimab Chemical Structure
    1/16
  • Lusvertikimab
  • Immobilized Human IL-7R alpha/CD127 Protein (ECD, His Tag) can bind Lusvertikimab. The EC50 for this effect is 3.8 ng/mL.
  • Flow Cytometry analysis of K562 cells labelling IL-7Ra/CD127 (red) with Lusvertikimab (anti-IL-7Ra/CD127) (HY-P99412). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG4 (S228P) kappa (HY-P99003). Black-Unlabelled control, cells without incubation with primary antibody.