PROTAC A515
PROTAC A515 is a SMARCA2 PROTAC degrader. PROTAC A515 promotes the ubiquitination and degradation of SMARCA2. PROTAC A515 can be used in cancer research.
(Pink: SMARCA2 ligand (HY-180932); Blue: VHL ligand (HY-168243); Black: linker).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2378056-72-3
- Formule: C55H68N12O7S
- Masse moléculaire:1041.27
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform PROTACs
MoreVoir tous les produits spécifiques à Isoform SWI/SNF Complex
More
Activité biologique
|
SMARCA2 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Calu-6 | GI50 |
12 nM
Compound: 15
|
Antiproliferative activity against human Calu-6 cells assessed as growth inhibition incubated for 7 days by celltiter glo 2.0 assay
Antiproliferative activity against human Calu-6 cells assessed as growth inhibition incubated for 7 days by celltiter glo 2.0 assay
|
[PMID: 38180485] |
Chemical Information
-
CAS No. 2378056-72-3
-
Masse moléculaire 1041.27
-
Formule C55H68N12O7S
-
SMILES
CC1=C(SC=N1)C2=CC=C([C@H](C)NC([C@H]3N(C[C@@H](C3)O)C([C@@H](C4=CC(OCCN5C[C@H](N(CC5)CCOC6=NC=CC(N7C8CN(C9=C(N)N=NC(C%10=C(C=CC=C%10)O)=C9)CC7CC8)=C6)C)=NO4)C(C)C)=O)=O)C=C2
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC A515 Related Classifications
HY-180931 Related Classifications
Powered by Bioz