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Cat. No.: HY-W740048

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Quinine-d₃

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Quinine-d₃ is the deuterium labeled Quinine (HY-D0143). Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100?mV with an IC₅₀ of 169 μM.

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CAS No.: 2734920-95-5
Formule: C₂₀H₂₁D₃N₂O₂
Masse moléculaire:327.44

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (244 KB)

Quinine-d₃ Chemical Structure

CAS No.: 2734920-95-5

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Activité biologique

Description

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In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2734920-95-5
Unlabeled Cas 130-95-0
Masse moléculaire 327.44
Formule C₂₀H₂₁D₃N₂O₂
SMILES

[H][C@]1([C@@H]2C[C@]([H])([N@@](CC2)C1)[C@@H](C3=CC=NC4=CC=C(C=C43)OC([2H])([2H])[2H])O)C=C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.