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United States

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Cat. No.: HY-123541

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Tec-IN-6

Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC₅₀ of 8.9 μM (His-FGF2/GST-NΔ173 Tec).

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CAS No.: 923762-87-2
Formule: C₁₉H₁₉N₃O₅
Masse moléculaire:369.37

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Tec-IN-6 Chemical Structure

CAS No.: 923762-87-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Tec-IN-6 (compound 6) is a FGF2 binding to Tec kinase inhibitor, with an IC₅₀ of 8.9 μM (His-FGF2/GST-NΔ173 Tec)^[1].

Chemical Information

CAS No. 923762-87-2
Masse moléculaire 369.37
Formule C₁₉H₁₉N₃O₅
SMILES

O=C(OCC(N=C1N2C(C)=CC=C1)=CC2=O)C3=C(C(C(OC)=O)=C(N3)C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Giuseppe La Venuta, et al. Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2. J Biol Chem. 2016 Aug 19;291(34):17787-803. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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