VU6032735
Based on 1 Customer Validation
VU6032735 is a potent and subtype-selective sperm-specific potassium channel 3 (SLO3) inhibitor with IC50 values of 165 nM (hSLO3) and 730 nM (mSLO3). VU6032735 also inhibits sodium channel and L-type calcium channel VU6032735 can sustain high tissue exposure in the fertilized oviduct. VU6032735 can be used for the research of contraception.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.26%
- Formule: C25H21F6N3O3
- Masse moléculaire:525.44
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Stockage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
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Activité biologique
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hSLO3 165 nM (IC50) |
mSLO3 730 nM (IC50) |
L-type calcium channel |
VU6032735 (10 μM, 1-2 h) significantly inhibits human sperm hyperactivated motility[1].
VU6032735 (0.01-1 μM) inhibits mouse SLO3-γ2 channels in HEK293 cells[1].
VU6032735 (10 μM) inhibits sodium channel and L-type calcium channel[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Masse moléculaire 525.44
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Formule C25H21F6N3O3
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Color White to off-white
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SMILES
O=C(C1=CC=C(OCC2=CC=C(OC(F)(F)F)C=C2)C=C1)N3CCN(C4=NC=C(C(F)(F)F)C=C4)CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Pureté et documentation
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Fiche technique (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VU6032735 Related Classifications
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