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Art. -Nr.: HY-185041

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CHD1L-IN-2

Name: CHD1L-IN-2
Brand: MedChemExpress
SKU: HY-185041
Price: 650.00 USD
Availability: InStock
Rating: 5 (1 reviews)

CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1251542-88-7
Formel: C₂₄H₂₄N₆O
Molecular Weight:412.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

CHD1L-IN-2 Chemical Structure

CAS. Nr.: 1251542-88-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells^[1]^[2].

Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen :

In Vitro

CHD1L-IN-2 (Compound 6.3) (72 h) has IC₅₀ values of 3.6 and 3.7 μM for SW620 and HCT116 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1251542-88-7
Molecular Weight 412.50
Formel C₂₄H₂₄N₆O
SMILES

O=C(NC1=CC=C(C=C1)NC2=NC(=NC(=C2)C)N3CCCC3)C4=CNC=5C=CC=CC54
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Daniel V. LABARBERA, et al. Small molecule inhibitors of oncogenic chd1l with preclinical activity against colorectral cancer. WO2023055763A2. 2023-04-06.

[2]. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022 Mar 10;65(5):3943-3961. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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