2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. CXCR3 antagonist 1

CXCR3 antagonist 1 (compound 6c) is a selective and non-cytotoxic CXCR3 antagonist (IC50=0.06 µM). CXCR3 antagonist 1 has potential in researching inflammatory diseases (including inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and diabetes).

For research use only. We do not sell to patients.

CXCR3 antagonist 1 Chemical Structure

CXCR3 antagonist 1 Chemical Structure

CAS No. : 870998-13-3

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CXCR3 antagonist 1 Related Antibodies

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Description

CXCR3 antagonist 1 (compound 6c) is a selective and non-cytotoxic CXCR3 antagonist (IC50=0.06 µM). CXCR3 antagonist 1 has potential in researching inflammatory diseases (including inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, and diabetes)[1].

IC50 & Target[1]

CXCR3

0.06 μM (IC50)

Molecular Weight

616.97

Formula

C30H32Cl3N5O3
CAS No.
SMILES

O=C(C1=CC(Cl)=CC=C1)NC2=CC(C(NCCC3=CC=C(C=C3Cl)Cl)=O)=CC=C2N4CCN(CCC4)C(NCC)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CXCR3 antagonist 1 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CXCR3 antagonist 1870998-13-3CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsHEK293inflammationmultiple sclerosisrheumatoid arthritisdiabetesInhibitorinhibitorinhibit

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