(+)-Cyclozonarone
(+)-Cyclozonarone is a benzoquinone derivative found in brown algae Dictyopteris undulata, with activity against T. cruzi epimastigotes, Tulahuen strains. (+)-Cyclozonarone inhibits growth of cancer and endothelial cells, and exhibits anti-leishmanial activity. (+)-Cyclozonarone can be used for the research of lung carcinoma, colon carcinoma, prostate carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 332858-46-5
- Formula: C21H24O2
- Molecular Weight:308.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
(+)-Cyclozonarone shows selective cytotoxicity toward MS-1 mouse endothelial cells with an IC50 of 0.1-0.5 μg/mL, and has IC50 values of 1-5 μg/mL for A-549 cells, 5 μg/mL for H-116 and PC-3 cells, and 1 μg/mL for HT-29 cells[1].
(+)-Cyclozonarone potently inhibits the growth of T. cruzi Tulahuen strain epimastigotes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 332858-46-5
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Molecular Weight 308.41
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Formula C21H24O2
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SMILES
C[C@@]12C3=CC(C(C=CC4=O)=O)=C4C=C3CC[C@@]1([H])C(C)(CCC2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(+)-Cyclozonarone Related Classifications
HY-184345 Related Classifications
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