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Art. -Nr.: HY-142972

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19(S)-HETE

Name: 19(S)-HETE
Brand: MedChemExpress
SKU: HY-142972
Price: 475.00 USD
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19(S)-HETE is an arachidonic acid metabolite produced by cytochrome P450 enzymes. 19(S)-HETE is a full orthosteric agonist of the prostacyclin (IP) receptor with an EC₅₀ value of 567 nM. 19(S)-HETE inhibits platelet activation and relaxation of vessels.

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CAS. Nr.: 115461-40-0
Formel: C₂₀H₃₂O₃
Molecular Weight:320.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (260 KB)

19(S)-HETE Chemical Structure

CAS. Nr.: 115461-40-0

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Biologische Aktivität

Beschreibung

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

19(S)-HETE (1 μM; 15 min) dose-dependently induces cAMP in MEG-01 cells with an EC₅₀ value of 520 nM^[1].
19(S)-HETE (1 μM-1 M) dose-dependently activates the IP receptor with an EC₅₀ value of 567 nM^[1].
19(S)-HETE (10 μM-1 M) displaces ³H-iloprost of IP receptor expressed COS-1 cells with a K_i value of 660 nM^[1].
19(S)-HETE (3 μM) relaxes arterial blood vessels and inhibits platelet activation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 115461-40-0
Molecular Weight 320.47
Formel C₂₀H₃₂O₃
SMILES

C[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Tunaru S, et al. Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor. PLoS One. 2016 Sep 23;11(9):e0163633. [Content Brief]

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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19(S)-HETE

(±)8(9)-EpETE

8,9-DiHETE

5,6-DiHETE

2-Hydroxyicosanoic acid

20-HETE Ethanolamide

14S(15R)-EET methyl ester

(±)15-HEDE

(±)12-HEPE

(±)5-HEPE

14(15)-EpETE

(±)5(6)-Epete methyl ester

(±)14(15)-EpEDE

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Bioz

19(S)-HETE

(±)8(9)-EpETE

8,9-DiHETE

5,6-DiHETE

2-Hydroxyicosanoic acid

20-HETE Ethanolamide

14S(15R)-EET methyl ester

(±)15-HEDE

(±)12-HEPE

(±)5-HEPE

14(15)-EpETE

(±)5(6)-Epete methyl ester

(±)14(15)-EpEDE

Alle Prostaglandin Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

19(S)-HETE Related Classifications

HY-142972 Related Classifications

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