Desmycosin
Based on 1 Customer Validation
Desmycosin is a macrolide antibiotic. Desmycosin exhibits biological activity against H. influenzae, S.aureus, S. pneumoniae, and S. pyogenes with MIC values of 4, 1, <0.125, and <0.125 µg/ml, respectively. Desmycosin is an acidic degradation product of tylosin.
For research use only. We do not sell to patients.
- Purity : 95.00%
- CAS No.: 11032-98-7
- Formula: C39H65NO14
- Molecular Weight:771.93
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
Chemical Information
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CAS No. 11032-98-7
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Appearance Solid
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Molecular Weight 771.93
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Formula C39H65NO14
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SMILES
O=CC[C@@H](C[C@H](C(/C=C/C(C)=C/[C@@H]([C@H](OC(C[C@H]([C@@H]1C)O)=O)CC)CO[C@H]2[C@@H]([C@@H]([C@@H]([C@H](O2)C)O)OC)OC)=O)C)[C@@H]1O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C)O)N(C)C)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (64.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (623 KB)
- English - EN (623 KB)
- Français - FR (623 KB)
- Deutsch - DE (623 KB)
- Norwegian - NO (623 KB)
- Español - ES (623 KB)
- Swedish - SV (623 KB)
- Italian - IT (623 KB)
- Korean - KR (623 KB)
- Portuguese - PT (623 KB)
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Handling Instructions (2659 KB)
References
[1]. Iveković D, et al., Electrochemical reduction of desmycosin, structure investigation and antibacterial evaluation of the resulting products. Eur J Pharm Sci. 2003 Apr;18(5):323-8. [Content Brief]
[2]. Thompson TS, et al., Tylosin A and desmycosin in honey by salting-out assisted liquid-liquid extraction and aqueous normal phase ultraperformance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2019 Sep;411(24):6509-6518. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2955 mL | 6.4773 mL | 12.9545 mL | 32.3864 mL |
| 5 mM | 0.2591 mL | 1.2955 mL | 2.5909 mL | 6.4773 mL | |
| 10 mM | 0.1295 mL | 0.6477 mL | 1.2955 mL | 3.2386 mL | |
| 15 mM | 0.0864 mL | 0.4318 mL | 0.8636 mL | 2.1591 mL | |
| 20 mM | 0.0648 mL | 0.3239 mL | 0.6477 mL | 1.6193 mL | |
| 25 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2955 mL | |
| 30 mM | 0.0432 mL | 0.2159 mL | 0.4318 mL | 1.0795 mL | |
| 40 mM | 0.0324 mL | 0.1619 mL | 0.3239 mL | 0.8097 mL | |
| 50 mM | 0.0259 mL | 0.1295 mL | 0.2591 mL | 0.6477 mL | |
| 60 mM | 0.0216 mL | 0.1080 mL | 0.2159 mL | 0.5398 mL |
Desmycosin Related Classifications
HY-W653770 Related Classifications
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