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Diclofenac deanol

(Synonyms: DDNL)
17 Cited Publications
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Based on 17 publication(s) in Google Scholar

Diclofenac deanol (DDNL) is a nonsteroidal anti-inflammatory drug with anti-inflammatory, analgesic and antipyretic activities. Diclofenac deanol has a more potent inhibitory effect on cyclooxygenase (COX)-2 than on COX-1. The solubility of diclofenac deanol is significantly higher than that of other diflunisal salts reported earlier. Diclofenac deanol has a wide range of potential applications in the medical field due to its biological activity and high water solubility.

For research use only. We do not sell to patients.

  • CAS No.: 81811-14-5
  • Formula: C18H22Cl2N2O3
  • Molecular Weight:385.28
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Diclofenac deanol Chemical Structure
    Diclofenac deanol Chemical Structure
  • Experimental Validation Results for Diclofenac deanol
  • Experimental Validation Results for Diclofenac deanol
  • Experimental Validation Results for Diclofenac deanol
  • Experimental Validation Results for Diclofenac deanol
CAS No.: 81811-14-5
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • Diclofenac deanol Chemical Structure
    Diclofenac deanol Chemical Structure
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    Diclofenac deanol purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 11;23(20):12066. [Abstract]

    Customer Validation
     KATOIII and KATO/DDP were treated with different concentration of Diclofenac (DCF) (0–1000 µM) for 48 h, and cell viability was assessed.

  • 1/16

    Diclofenac deanol purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 11;23(20):12066. [Abstract]

    Customer Validation
     The KATO/DDP cells were treated with Cisplatin alone or cisplatin in combination with Diclofenac (DCF) at 10 or 20 µM for 24 h, at 37 °C. The apoptosis cells were detected by using annexin V and PI staining and analyzed by flow cytometer.

  • 1/16

    Diclofenac deanol purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 11;23(20):12066. [Abstract]

    Customer Validation
     The combination effect of Diclofenac (DCF) (0, 5, 10, 20 μM) and Cisplatin on the expression of cleaved PARP in KATO/DDP cells was examined by Western blot analysis.

  • 1/16

    Diclofenac deanol purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2022 Oct 11;23(20):12066. [Abstract]

    Customer Validation
     The formation of autophagic vacuoles in KATO/DDP cells increased from 27% to 39% and 45% in cotreatments involving cisplatin and Diclofenac (DCF) at 10 and 20 μM, respectively, when compared with treatment of cisplatin alone.

  • Diclofenac deanol