cis-ACBD
Based on 1 Customer Validation
cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 73550-55-7
- Formula: C6H9NO4
- Molecular Weight:159.14
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 73550-55-7
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Appearance Solid
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Molecular Weight 159.14
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Formula C6H9NO4
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Color White to off-white
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SMILES
OC([C@]1(C[C@@H](C1)C(O)=O)N)=O
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Synonyms
cis-1-Aminocyclobutane-1,3-dicarboxylic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 62.5 mg/mL (392.74 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8. [Content Brief]
[2]. Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.2838 mL | 31.4189 mL | 62.8378 mL | 157.0944 mL |
| 5 mM | 1.2568 mL | 6.2838 mL | 12.5676 mL | 31.4189 mL | |
| 10 mM | 0.6284 mL | 3.1419 mL | 6.2838 mL | 15.7094 mL | |
| 15 mM | 0.4189 mL | 2.0946 mL | 4.1892 mL | 10.4730 mL | |
| 20 mM | 0.3142 mL | 1.5709 mL | 3.1419 mL | 7.8547 mL | |
| 25 mM | 0.2514 mL | 1.2568 mL | 2.5135 mL | 6.2838 mL | |
| 30 mM | 0.2095 mL | 1.0473 mL | 2.0946 mL | 5.2365 mL | |
| 40 mM | 0.1571 mL | 0.7855 mL | 1.5709 mL | 3.9274 mL | |
| 50 mM | 0.1257 mL | 0.6284 mL | 1.2568 mL | 3.1419 mL | |
| 60 mM | 0.1047 mL | 0.5236 mL | 1.0473 mL | 2.6182 mL | |
| 80 mM | 0.0785 mL | 0.3927 mL | 0.7855 mL | 1.9637 mL | |
| 100 mM | 0.0628 mL | 0.3142 mL | 0.6284 mL | 1.5709 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
cis-ACBD Related Classifications
HY-100616 Related Classifications
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