Fibronectin CS1 Peptide
Based on 1 Customer Validation
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models.
For research use only. We do not sell to patients.
- Purity: 99.10%
- CAS No.: 136466-51-8
- Formula: C38H64N8O15
- Molecular Weight:872.96
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
824 μM
Compound: 1
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Antagonist activity at integrin alpha4beta1 receptor in human CCRF-CEM cells assessed as inhibition of cell adhesion to fibronectin after 1 hr by calcein AM staining-based fluorescence assay
Antagonist activity at integrin alpha4beta1 receptor in human CCRF-CEM cells assessed as inhibition of cell adhesion to fibronectin after 1 hr by calcein AM staining-based fluorescence assay
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10.1039/C1MD00229E |
Chemical Information
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CAS No. 136466-51-8
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Appearance Solid
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Molecular Weight 872.96
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Formula C38H64N8O15
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Color White to off-white
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Sequence
Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr
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Sequence Shortening
EILDVPST
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (114.55 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1455 mL | 5.7276 mL | 11.4553 mL | 28.6382 mL |
| 5 mM | 0.2291 mL | 1.1455 mL | 2.2911 mL | 5.7276 mL | |
| 10 mM | 0.1146 mL | 0.5728 mL | 1.1455 mL | 2.8638 mL | |
| 15 mM | 0.0764 mL | 0.3818 mL | 0.7637 mL | 1.9092 mL | |
| 20 mM | 0.0573 mL | 0.2864 mL | 0.5728 mL | 1.4319 mL | |
| 25 mM | 0.0458 mL | 0.2291 mL | 0.4582 mL | 1.1455 mL | |
| 30 mM | 0.0382 mL | 0.1909 mL | 0.3818 mL | 0.9546 mL | |
| 40 mM | 0.0286 mL | 0.1432 mL | 0.2864 mL | 0.7160 mL | |
| 50 mM | 0.0229 mL | 0.1146 mL | 0.2291 mL | 0.5728 mL | |
| 60 mM | 0.0191 mL | 0.0955 mL | 0.1909 mL | 0.4773 mL | |
| 80 mM | 0.0143 mL | 0.0716 mL | 0.1432 mL | 0.3580 mL | |
| 100 mM | 0.0115 mL | 0.0573 mL | 0.1146 mL | 0.2864 mL |
Fibronectin CS1 Peptide Related Classifications
HY-P1816 Related Classifications
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