DNDI-6148
Based on 1 Customer Validation
DNDI-6148 is a novel preclinical candidate for the research of visceral leishmaniasis.
For research use only. We do not sell to patients.
- Purity: 99.54%
- CAS No.: 2243909-59-1
- Formula: C16H14BN5O3
- Molecular Weight:335.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Parasite Isoforms
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Biological Activity
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Leishmania |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | CC50 |
>64 μM
Compound: 23; DNDI-6148
|
Cytotoxicity against human MRC5 cells measured after 3 days by resazurin staining based fluorometric analysis
Cytotoxicity against human MRC5 cells measured after 3 days by resazurin staining based fluorometric analysis
|
[PMID: 34711050] |
| Peritoneal macrophage | CC50 |
>64 μM
Compound: 23; DNDI-6148
|
Cytotoxicity against mouse primary peritoneal macrophages measured after 3 days by resazurin staining based fluorometric analysis
Cytotoxicity against mouse primary peritoneal macrophages measured after 3 days by resazurin staining based fluorometric analysis
|
[PMID: 34711050] |
Chemical Information
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CAS No. 2243909-59-1
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Appearance Solid
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Molecular Weight 335.13
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Formula C16H14BN5O3
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Color Off-white to light yellow
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SMILES
O=C(C1=C(C)N(C2=NC=CC=C2)N=N1)NC3=CC=C4C(B(O)OC4)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)