1. Epigenetics
  2. Histone Acetyltransferase
    Histone Demethylase
  3. DS17701585

DS17701585 

Cat. No.: HY-143443
Handling Instructions

DS17701585 (Compound 11) is a highly selective, orally active EP300 and CBP inhibitor with IC50 values of 0.040, 0.15, 0.45 and 0.70 µM against CBP, EP300, H3K27 and SOX2. DS17701585 can be used for cancer research.

For research use only. We do not sell to patients.

DS17701585 Chemical Structure

DS17701585 Chemical Structure

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Description

DS17701585 (Compound 11) is a highly selective, orally active EP300 and CBP inhibitor with IC50 values of 0.040, 0.15, 0.45 and 0.70 µM against CBP, EP300, H3K27 and SOX2. DS17701585 can be used for cancer research[1].

IC50 & Target

CBP

0.040 μM (IC50)

EP300

0.15 μM (IC50)

H3K27

0.45 μM (IC50)

SOX2

0.70 μM (IC50)

Molecular Weight

482.55

Formula

C24H26N4O5S

SMILES

O=C([[email protected]@H](C1)N(C(C2(C3=CC=C(OC)C=C3)CCCC2)=O)CS1(=O)=O)NC4=CC=CC5=C4C=NN5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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DS17701585
Cat. No.:
HY-143443
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