1. Epigenetics
  2. Histone Acetyltransferase Histone Demethylase
  3. DS17701585

DS17701585 (Compound 11) is a highly selective, orally active EP300 and CBP inhibitor with IC50 values of 0.040, 0.15, 0.45 and 0.70 µM against CBP, EP300, H3K27 and SOX2. DS17701585 can be used for cancer research.

For research use only. We do not sell to patients.

DS17701585 Chemical Structure

DS17701585 Chemical Structure

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Description

DS17701585 (Compound 11) is a highly selective, orally active EP300 and CBP inhibitor with IC50 values of 0.040, 0.15, 0.45 and 0.70 µM against CBP, EP300, H3K27 and SOX2. DS17701585 can be used for cancer research[1].

IC50 & Target

H3K27

0.45 μM (IC50)

SOX2

0.70 μM (IC50)

EP300

0.04 μM (IC50)

CBP

0.15 μM (IC50)

Molecular Weight

482.55

Formula

C24H26N4O5S

SMILES

O=C([C@@H](C1)N(C(C2(C3=CC=C(OC)C=C3)CCCC2)=O)CS1(=O)=O)NC4=CC=CC5=C4C=NN5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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DS17701585 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DS17701585
Cat. No.:
HY-143443
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